Endocrine Abstracts

Introduction: Graves’ dermopathy (also known as pretibial myxedema, thyroid dermopathy, Jadassohn-Dösseker disease or myxedema tuberosum) is a rare extrathyroidal manifestation of Graves’ disease, which is almost always associated with Graves’ ophthalmopathy. Although pretibial myxedema is the most frequent localization of Graves’ dermopathy, the involvement of toes with or without the involvement of pretibial area may occur.Obje...

Frequently seen in connection with thyroid disease, exophtalmic syndrome has a much large spectrum of differential diagnosis including numerous local and general aetiologies. Conditions such as mucoceles of paranasal sinuses don’t have always nasal or sinus symptoms but may present with ophthalmological manifestations.A 50-year-old woman presented for a 2-months history of right eye proptosis with upper eyelid swelling, periorbital pain, occasionall...

IntroductionAnti-thyroid drugs (ATDs) are the first line treatment in Europe for hyperthyroidism due to Graves’ disease (GD). Adding levothyroxine to ATDs, so called block and replace therapy (BRT) is still controversial.AimTo follow up the outcomes after treating patients with Graves’ disease in a block and replace regimen.Patients & methodsA prospe...

IntroductionSilent corticotroph adenoma represent an uncommon subtype of nonfunctioning adenoma, immunoreactive for ACTH, without clinical or biochemical evidence of hypercortisolism and unclear pathogenesis. Usually, they present with local mass effect (visual deterioration being the most common) and endocrine dysfunctions. They carry a more aggressive behavior, particularly upon earlier recurrence.Case presentation<p class="a...

Background and objective: The purpose of this study was to retrospectively analyse the clinical, imaging and hormonal features, as well as the therapeutic outcomes in a series of consecutive patients presenting with pituitary apoplexy (PA).Design: We retrospectively reviewed 71 case-records of patients with PA admitted during 2019 in a single tertiary endocrinology center.Results: ...

Introduction: The association between autoimmune thyroid disease and thyroid cancer is a dynamic field regarding the prevalence data and the common pathogenic background.Aim: We report a sixth decade women case with a 1 year history of Graves’ disease that was discovered with an aggressive differentiated thyroid carcinoma.Case report: M.E. 56-year-old female has a 10 months history of daily medium dose of thyamazolum which was...

Background: Craniopharyngioma is a rare, mostly benign tumor of the central nervous system, generally associated with important morbidity.Aim: To study the clinical characteristics and treatment outcome in adult patients.Methods:: Adult patients diagnosed with craniopharyngioma between 1980 and 2012, followed-up in the Pituitary and Neuroendocrine Department of the ‘C.I.Parhon’ National Institute of Endocrinology in Bucha...

Background: Oral glucose tolerance test (OGTT) is a step in the evaluation of children and adolescents with tall stature for documenting a possible autonomous GH secretion.Aim: Assessment of GH dynamics in OGTT in children and adolescents with tall stature in various stages of pubertal development for documenting a possible autonomous GH secretion.Method: Our study included 44 subjects, 18 girls and 26 boys, with age between 6.5 an...